The Ellison Medical Foundation is pleased to support the research of 25 exceptional young scientists who have been named New Scholars in Aging for 2013.
Aging of the Nervous System
The number of stem cells in the brain, as in other tissues, decreases with age. EMF-supported research seeks to understand why this happens and how the body compensates for the effects of aging. Image from the Enikolopov lab, CSHL.
Naked Mole Rat
Even though they're about the same size as a mouse, naked mole rats have a lifespan that is nine times longer, and they almost never develop cancer. Work in Rochelle Buffenstein's lab is aimed at understanding how this is accomplished.
Stem Cells and Aging
EMF-sponsored research is exploring how stem cells, such as these germline stem cells at the tip of a Drosophila ovary, are altered as their surrounding "niche" changes over the lifespan. Image from Dr. Leanne Jones, Salk Institute.
Cognitive Changes with Aging
Neuroscience research supported by the EMF is revealing how brain networks and cognitive functions change with aging. Research study in the Gazzaley Lab, UCSF.
Responses to Cellular Stress during Aging
Built-in protection mechanisms respond to age-related cellular stress and tissue damage. Projects supported by EMF seek to understand and ultimately harness these mechanisms to enhance healthy aging. (Image from the Tzima lab, UNC.)
Cellular Senescence and Aging
EMF-supported research is illuminating how the accumulation of non-dividing senescent cells contributes to decline of tissue function with advancing age. Senescent human fibroblasts (Weinberg lab, MIT).
The Lawrence Ellison Foundation supports basic biomedical research on aging relevant to understanding lifespan development processes and age-related diseases and disabilities.
About the Aging Program
The world's 60-and-over population increased by more than 12 million persons in 1995 alone, reaching a total of 550 million.
By the year 2025, 1.2 billion people will be 60 or older. Improvements in health care and disease prevention have the potential to create economic benefit to, and to dramatically improve the quality of life of, millions of individuals. Significant breakthroughs in understanding the basic biological processes that underlie aging and age-related diseases are the best hope we have for achieving genuine prevention or amelioration of age-related debilitation and disease.
About the Neuroscience Program
Like the Foundation's Biology of Aging Scholars program, the Neuroscience Scholars program was designed to provide researchers with the support and resources to develop innovative research programs aimed at gaining insight into the fundamental molecular and cellular mechanisms that underlie normal biological function, and when dysfunctional, lead to illness.